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HI SEQ 2500
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Bacterial Genomes

Genome of an organism is the blueprint and sequencing is the most ba sic step. Subsequent to sequencing is annotation that makes the genome meaningful.These processes collectively make DNA sequences as a knowl edge base of all genic regions and other related information. Sanger in vented a DNA sequencing method[1] in late 70’s that immediately became the choicest method of sequencing.


Whole Genome Bisulphite Sequencing (WGBS)

Whole Genome Bisulphite Sequencing (WGBS) is a NGS based genome wide methylation profiling application. It is considered as a gold standard to identify and quantify the methylation levels of the entire genome. Epigenome is considered as an other layer of genetic information over the genome [1]. Recent research efforts on bring about environmentally induced genetic changes [2,3]. DNA methylation and histone modifications


Genotyping with RAD and ddRAD Sequencing

Whole Genome Bisulphite Sequencing (WGBS) is a NGS based genome wide methylation profiling application. It is considered as a gold standard to identify and quantify the methylation levels of the entire genome. Epigenome is considered as an other layer of genetic information over the genome [1]. Recent research efforts on bring about environmentally induced genetic changes [2,3]. DNA methylation and histone modifications are the two major epigenetic modifications that plays a vital role in the cell fate and development.


Exome Sequencing and Data Analysis

The protein coding, or exonic regions, constitute ~1.5% of the human genome. An estimated 85% of known variations/mutations underlying disease-related traits occur in the exons of the genome [1]. Mutations identified in the exonic regions are typically actionable compared to variations that occur in non-coding regions. Exome sequencing involves selective capture and sequencing of these protein coding regions of the genome. Compared to whole genome sequencing, exome sequencing is more cost effective and also provides better per base coverage.


RNA Sequencing

RNA-Seq is a high-throughput sequencing based approach for transcriptome profiling. The information contained in the genome (DNA) is transcribed into RNA molecules by a process called transcription. The transcribed regions of the genome encode different types of RNA molecules, like mRNA, tRNA, rRNA, miRNA, lincRNA, snoRNA and others. The set of transcribed RNA products constitute the transcriptome. In humans, the transcriptome represents an estimated 5% of the genome (Frith et al, 2005).


De novo Transcriptome Sequencing & Analysis

Over the past few years, the next-generation sequencing (NGS) methods have revolutionized functional genomics research. Due to the comparative high cost of sequencing large and complex genomes, RNA sequencing (RNA-Seq) has emerged as a cost-effective means of rapidly acquiring functional sequence information for non-model systems. RNA-Seq is a powerful tool for simultaneous transcriptome characterization and differential gene expression (DGE) analysis in a single cell type, tissue type, or entire organism under defined conditions [1]. In the past few years, RNA-Seq has helped in decoding transcriptomes of various species, including several plants, birds, insects and animals for which no reference genome is available [1-9]. RNA-seq also provides data about alternative splicing, strand-specific expression, expression of unannotated exons (or genes), and identification of fusion genes in cancer. It also provides gene expression data at a greater sensitivity than microarrays.


NextGen LIMS

NextGen LIMS is an end-to-end workflow management system for a next-gen sequencing labs. It provides an automated workflow for key functions within a next-gen lab: Project Management, Sample Management, Library Management and Sequencing Run Management. It tracks the end-to-end project progression - samples, libraries and sequencing runs through a set of pre -defined workflows; thus reducing manual intervention.


Customer Publications

  • Khushboo J. Nagdev, Sharda P. Bhagchandani, Shradha S. Bhullar, Rajkumar C. Kapgate, Rajpal S. Kashyap, Nitin H. Chandak, Hatim F. Daginawala, Hemant J. Purohit, Girdhar M. TaoriRapid Diagnosis and Simultaneous Identification of Tuberculous and Bacterial Meningitis by a Newly Developed Duplex Polymerase Chain Reaction Indian Journal of Microbiology June 2015, Volume 55, Issue 2, pp 213-218
  • Krishanender Dinesh, Archana Verma, Ishwar Das Gupta, Yash Pal Thakur, Nishant Verma, Ashwani Arya. Identification of polymorphism in exons 7 and 12 of lactoferrin gene and its association with incidence of clinical mastitis in Murrah buffalo Tropical Animal Health and Production .April 2015, Volume 47, Issue 4, pp 643-647.
  • Reshma Silvester, Deborah Alexander, Mohamed Hatha Abdulla AmmanamveetilPrevalence, antibiotic resistance, virulence and plasmid profiles of Vibrio parahaemolyticus from a tropical estuary and adjoining traditional prawn farm along the southwest coast of IndiaAnnals of Microbiology, Springer Berlin Heidelberg. DOI 10.1007/s13213-015-1053-x. March 2015
  • S Sharma, S M Javadekar, M Pandey, M Srivastava, R Kumari and S C Raghavan.Homology and enzymatic requirements of microhomology-dependent alternative end joining. Cell Death and Disease (2015) 6, e1697; doi:10.1038/cddis.2015.58 Published online 19 March 2015
  • V. F. Sanu, S. Bijoy Nandan, J. Deepak, M. HarikrishnanMolecular identification and systematic assessment of Labidocera madurae A. Scott, 1909 (calanoid copepod) from Lakshadweep Archipelago, southwest coast of India, based on mitochondrial COI gene sequencesSpringer Berlin Heidelberg, Marine Biodiversity. DOI10.1007/s12526-015-0326-8. (11 Mar 2015).
  • T. E. Sheeja, K. Deepa, R. Santhi, B. Sasikumar.Comparative Transcriptome Analysis of Two Species of Curcuma Contrasting in a High-Value Compound Curcumin: Insights into Genetic Basis and Regulation of Biosynthesis.Plant Molecular Biology Reporter, Springer US. DOI10.1007/s11105-015-0878-6.
  • N. Sudhakar, C. George Priya Doss, D. Thirumal Kumar, Chiranjib Chakraborty, Kushi Anand & M. SureshDeciphering the impact of somatic mutations in exon 20 and exon 9 of PIK3CA gene in breast tumors among Indian women through molecular dynamics approachJournal of Biomolecular Structure and Dynamics DOI:10.1080/07391102.2015.1007483
  • EA George, S Sankar, MV Jesudasan, C Sudandiradoss, B NandagopalMolecular characterization of CTX-M type Extended Spectrum Beta Lactamase producing E. coli isolated from humans and the environment. Indian Journal of Medical Microbiology,Year : 2015, Vol:33,Issue : 5, Pa: 73-79, DOI: 10.4103/0255-0857.150896.
  • YPS Malik, N Kumar, V Rawat, K Sharma, A Kumar, M Singhai, M Kumar Detection and distribution pattern of prevalent genotypes of Hepatitis-C virus among chronic hepatitis patients from Kumaon region of Uttarakhand, India. Indian Journal of Medical Microbiology DOI: 10.4103/0255-0857.148838 Year :2015,Vol: 33,Issue : 5,Pa:161-163
  • Mashhoor K., Lazar K.V., ShanasS. and Ramesh N. Mitochondrial DNA analysis revealed Gondwanan origin of the Common Evening Brown butterfly, Melanitis leda (Lepidoptera: Nymphalidae). Journal of Agricultural Technology 2015 Vol. 11(3):649-656. ISSN 1686-9141.
  • Susheel Kumar Sharma, P. Vignesh Kumar, A. Swapna Geetanjali, Khem Bahadur Pun, Virendra Kumar Baranwal. Subpopulation level variation of banana streak viruses in India and common evolution of banana and sugarcane badnaviruses. Virus Genes,Springer US. DOI: 10.1007/s11262-015-1179-8.
  • Shyamalina Haldar and Sanghamitra Sengupta.Impact of plant development on the rhizobacterial population of Arachis hypogaea: a multifactorial analysis.. DOI: 10.1002/jobm.201400683: 9 JAN 2015
  • Aggarwal RK, Dawar C, Das S, Sharma S. 2015.Draft genome sequences of two drug-resistant isolates of Pseudomonas aeruginosa obtained from keratitis patients in India. Genome Announc 3(1):e01404-14. doi:10.1128/genomeA.01404-14.
  • Gudikandula Krishna, Burra Samatha, S. V. S. S. S. L. Hima Bindu Nidadavolu, Metuku Ram Prasad, Byram Rajitha, and Maringanti Alha Singara Charaya.Macrofungi in Some Forests of Telangana State, India. Journal of Mycology. Volume 2015 (2015), Article ID 382476, 7 pages.
  • Ambardar, Sheetal, Naseer Sangwan, A. Manjula, J. Rajendhran, P. Gunasekaran, Rup Lal, and JyotiVakhlu. Identification of bacteria associated with underground parts of Crocus sativus by 16S rRNA gene targeted metagenomic approach. World Journal of Microbiology and Biotechnology 30, no. 10 (2014): 2701-2709.
  • Bindu, P. U., and C. D. Sebastian. Genetic structure of mitochondrial cytochrome oxidase subunit I gene of the mosquito, Armigeressubalbatus. International Journal of Research 1, no. 10 (2014): 49-56.
  • Reshamwala, Shamlan, Sandip K. Pagar, Vishal S. Velhal, Vijay M. Maranholakar, Vishal G. Talangkar, and Arvind M. Lali. Construction of an efficient Escherichia coli whole-cell biocatalyst for d-mannitol production. Journal of Bioscience and Bioengineering (2014).
  • Grewal, Simmi, and JyotiVakhlu.Assessment of Fungal Diversity and Screening for Antimicrobial Producing Fungi from the Soil Known for its Medicinal Value. American Journal of Ethnomedicine 1, no. 4 (2014): 231-243..
  • Manimekalai, Ramaswamy, Roshna Othayoth Mailapravan, Gangaraj Kariyath Palliyath, Smita Nair, Rasappa Viswanathan, and R. Rabindran. Molecular characterization based on spermidine/putrescine ABC transporter gene of sugarcane grassy shoot (16SrXI), coconut root wilt (16SrXI), aster yellows (16SrI) and brinjal little leaf (16SrVI) phytoplasmas. Phytopathogenic Mollicutes 4, no. 1 (2014): 16-21.
  • Soman, Manju, Sreeja R. Nair, M. Mini, Binu K. Mani, and Siju Joseph. Isolation and polymerase chain reaction-based identification of Riemerellaanatipestifer from ducks in Kerala, India. Veterinary World 7, no. 10 (2014): 765-769.
  • Lalhmangaihi, Ralte, Souvik Ghatak, Ramachandra Laha, Guruswami Gurusubramanian, and Nachimuthu Senthil Kumar.Protocol for Optimal Quality and Quantity Pollen DNA Isolation from Honey Samples. Journal of biomolecular techniques: JBT (2014).
  • Dev, Suma Arun, E. M. Muralidharan, P. Sujanapal, and M. Balasundaran. Identification of market adulterants in East Indian sandalwood using DNA barcoding. Annals of Forest Science 71, no. 4 (2014): 517-522.
  • Najm, Mohammad Zeeshan, Salman Akhtar, Istaq Ahmad, Shilpi Chattopadhyay, Nasar Mallick, Sarah Siddiqui, Shuaib Zaidi, Waseem Ahmad Siddiqui, and Syed Akhtar Husain. Mutation and protein expression analysis of CYP1A1 gene—a study on female breast cancer cases from India. Tumor Biology 35, no. 3 (2014): 1965-1971.
  • Birmole, Radhika, Swamini Patade, Vishwas Sirwaiya, and Firdaus Bargir. Biodegradation study of reactive blue 172 by DW01 Isolated from lake sediment. Indian J. Sci. Res 5, no. 1 (2014): 139-152.
  • Mohan. V, K. Saranya Devi, R. Srinivasan, and K.Sushamani. In-vitro Evaluation of Chromium Tolerant Plant Growth Promoting Bacteria from Tannery Sludge Sample, Dindugal, Tamil Nadu, India. Int. J. Curr. Microbiol. App. Sci 3, no. 10 (2014): 336-344.
  • Malik, Yashpal Singh, Naveen Kumar, Kuldeep Sharma, Souvik Ghosh, Krisztián Bányai, Ganesh Balasubramanian, Nobumichi Kobayashi, and Jelle Matthijnssens. Molecular analysis of non structural rotavirus group A enterotoxin gene of bovine origin from India. Infection, Genetics and Evolution 25 (2014): 20-27.
  • Yadav, Shashi, Dev Kumar Verma, Pravata Kumar Pradhan, Anoop Kumar Dobriyal, and Neeraj Sood. Phenotypic and genotypic identification of Aeromonas species from aquatic environment. Int. J. Aqu. Sci 5, no. 1 (2014): 3-20.
  • Maheswaran.S, S.S.Dasuru, A.Rama Chandra Murthy, B.Bhuvaneshwari, V.Ramesh Kumar, G.S.Palani, Nagesh R.Iyer, Sarayu Krishnamoorthy, and S.Sandhya. Strength improvement studies using new type wild strain Bacillus cereus on cement mortar. CURRENT SCIENCE 106, no. 1 (2014): 50.
  • Patagundi, Basavaraj.I, C.T.Shivasharan, and B.B.Kaliwal. Isolation and Characterization of Cellulase producing bacteria from Soil. Int. J. Curr. Microbiol. App. Sci 3, no. 5 (2014): 59-69.
  • Rajan, Iyyappan, Remitha Rabindran, N. Nithya, T. Lakshmipriya, P.R. Jayasree, and P.R.M. Kumar. Assessment of cell cycle phase-specific effects of zerumbone on mitotically synchronous surface cultures of Physarum polycephalum. Protoplasma (2014): 1-11.
  • Singh, Satbir, and Bijender Kumar Bajaj. Medium Optimization for Enhanced Production of Protease with Industrially Desirable Attributes from Bacillus subtilis K-1. Chemical Engineering Communications just-accepted (2014).
  • Brahmacharimayum, Bharati, and Pranab Kumar Ghosh. Sulfate bioreduction and elemental sulfur formation in a packed bed reactor. Journal of Environmental Chemical Engineering (2014).
  • Ravishankar, Vigneshwaran, Ahmed Ahmed, Ulaganathan Sivagnanam, Krishnaraja Muthuraman, Anbarasu Karthikaichamy, Herald A. Wilson, Ajay Devendran, Rudy A. Hartskeerl, and Stephen ML Raj. Evolution of the RNase PRNA structural domain in Leptospira spp. Research in microbiology (2014).
  • Nidheesh.T, Pal Gaurav Kumar, and P.V. Suresh. Enzymatic degradation of chitosan and production of d-glucosamine by solid substrate fermentation of exo-β-d-glucosaminidase (exochitosanase) by Penicilliumdecumbens CFRNT15. International Biodeterioration & Biodegradation 97 (2015): 97-106.
  • Swetha.V.P, V.A.Parvathy, T.E.Sheeja, and B.Sasikumar. DNA Barcoding for Discriminating the Economically Important Cinnamomumverum from Its Adulterants. Food Biotechnology 28, no. 3 (2014): 183-194.
  • Juliane Mooz, Tripat Kaur Oberoi-Khanuja, Gregory S. Harms, Weiru Wang, Bijay S.Jaiswal, Somasekar Seshagiri, Ritva Tikkanen and Krishnaraj, Rajalingam, Dimerization of the kinase ARAF promotes MAPK pathway activation and cell migration. Science Signaling, August 5, 2014, 7 (337), ra73. [doi: 10.1126/scisignal.2005484],ISSN 1937-9145.
  • V.A.Parvathy, V.P.Swetha, T.E.Sheeja, N.K.Leela, B.Chempakam & B.Sasikumar, DNA Barcoding to Detect Chilli Adulteration in Traded Black Pepper Powder. Food Biotechnology. Volume 28, Issue 1, 2014, DOI:10.1080/08905436.2013.870078 pages 25-40.
  • Jalaja Vidya, Mrudula Vasudevan Ushasree, Ashok Pandey, Effect of surface charge alteration on stability of l-asparaginase II from Escherichia sp. Enzyme and Microbial Technology Volume 56, 5 March 2014, Pages 15–19.
  • Vasudevan Gowthaman, Sambhu Dayal Singh, Kuldeep Dhama, Rajamani Barathidasan, Basavaraj S. Mathapati, Palani Srinivasan, Sellappan Saravanan, Muthannan Andavar Ramakrishnan, Molecular detection and characterization of infectious laryngotracheitis virus (Gallid herpesvirus-1) from clinical samples of commercial poultry flocks in India. Journal of Parasitic Diseases February 2014, DOI10.1007/s13337-014-0206-z, ISSN 2347-3517.
  • Nibedita Rana, Basanta K.Das, Morphometric and molecular identification of Paradactylogyrus catlaius (Thapar 1948) in Catla catla (Hamilton 1822). Journal of Parasitic Diseases, February 2014, DOI10.1007/s12639-014-0437-3, ISSN0975-0703.
  • Abdul Kareem Abdulrazak Al-kazaz, Sequence Variation and Phylogenetic Relationships Among Ten Iraqi Rice Varieties Using RM171 Marker Iraqi Journal of Science, 2014, Vol 55, No.1, pp:145-150.
  • Mohammad Zeeshan Najm, Salman Akhtar, Istaq Ahmad, Shilpi Chattopadhyay, Nasar Mallick, Sarah Siddiqui, Shuaib Zaidi, Waseem Ahmad Siddiqui, Syed Akhtar Husain, Mutation and protein expression analysis of CYP1A1 gene—a study on female breast cancer cases from India. Tumor Biology ,March 2014, Volume 35, Issue 3, pp 1965-1971.
  • Yashpal Singh Malik, Naveen Kumar, Kuldeep Sharma, Souvik Ghosh, Krisztián Bányai, Ganesh Balasubramanian, Nobumichi Kobayashi, Jelle Matthijnssens, Molecular analysis of non structural rotavirus group A enterotoxin gene of bovine origin from India. Infection, Genetics and Evolution Available online 16 April 2014.
  • Shashi Yadav, Dev Kumar Verma, Pravata Kumar Pradhan, Anoop Kumar Dobriyal and Neeraj Sood, Phenotypic and genotypic identification of Aeromonas species from aquatic environment. International Journal of Aquatic Science ISSN: 2008-8019 Vol. 5, No. 1, 3-20, 2014.
  • S.O.Sadashiv and B.B.Kaliwa, Isolation, characterization and antibiotic resistance of Bacillus sps. from bovine mastitis in the region of north Karnataka, India. Int.J.Curr.Microbiol.App.Sci (2014) 3(4): 360-373.
  • Larance Ronsard,, Sneh Lata, Jyotsna Singh, Vishnampettai G.Ramachandran, Shukla Das, Akhil C.Banerjea, Molecular and Genetic Characterization of Natural HIV-1 Tat Exon-1 Variants from North India and Their Functional Implications. PLOS ONE, Jan 2014 Vol 9 Isssue 1
  • Shukla.S, Shukla.S.K, Sharma.R and Kumar.A (2014), Identification of Mycobacterium species from apparently healthy freshwater aquarium fish using partial sequencing and PCR-RFLP analysis of heat shock protein (hsp65) gene. Journal of Applied Ichthyology, DOI: 10.1111/JAI.12415.
  • Iyyappan Rajan, Remitha Rabindran, N. Nithya, T. Lakshmipriya, P.R. Jayasree, P.R. M. Kumar, Assessment of cell cycle phase-specific effects of zerumbone on mitotically synchronous surface cultures of Physarum polycephalum. Protoplasma, DOI.January 2014.
  • P.K.Anil Kumar, P.V. Suresh, Biodegradation of Shrimp Biowaste by Marine Exiguobacterium sp. CFR26M and Concomitant Production of Extracellular Protease and Antioxidant Materials: Production and Process Optimization by Response Surface Methodology. Marine Biotechnology, April 2014, Volume 16, Issue 2, pp 202-218.
  • Krishna, Vamshi, Siju Joseph, R. Ambily, M. Mini, Liya Anto, and Sheethal G. Mohan. Cloning and sequencing of the virulent gene LipL32 of Leptospira interrogans serovar Autumnalis. Veterinary World 6, no. 4 (2013): 193-195.
  • Amitabha Chaudhuri, Nicholas S Wilson, Becky Yang, Andres Paler Martinez, Jinfeng Liu, Catherine Zhu, Nicole Bricker, Suzana Couto, Zora Modrusan, Dorothy French, James Cupp and Avi Ashkenazi Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages. Immunology and Cell Biology 2 July 2013 91, 451–460; doi:10.1038/icb.2013.27.
  • Naveen Sathyan, Rosamma Philip, E. R. Chaithanya, P. R. Anil Kumar, V. N. Sanjeevan, and I. S. Bright Singh, Characterization of Histone H2A Derived Antimicrobial Peptides, Harriottins, from Sicklefin Chimaera Neoharriotta pinnata (Schnakenbeck, 1931) and Its Evolutionary Divergence with respect to CO1 and Histone H2A,ISRN Molecular Biology,Volume 2013 (2013), Article ID 930216, 10 pages ,
  • Malik.Y.S, Kumar.N, Sharma.K, Haq.A.A, Kumar.A, Prasad.M (2013), Sequence and Phylogenetic Analysis of Bovine Rotavirus Isolates (G6 Genotypes) from India. Adv. Anim. Vet. Sci.1 (1): 41-43 ISSN: 2307 –8316.
  • Leya Thomas, Raveendran Sindhu, Ashok Pandey, Identification and characterization of a highly alkaline and thermotolerant novel xylanase from Streptomyces sp. Biologia, December 2013, Volume 68, Issue 6, pp 1022-1027 .
  • DebR, SinghU KumarS, TyagiS, SharmaA, KumarA, SengarG, SinghR(2013). Characterization and Evaluation of BL41 Microsatellite MarkerAssociated with Milk Fat and Protein Percentage among Frieswal (HF x Sahiwal ) Cattle of Indian Origin. Adv. Anim.Vet. Sci. 1 (3): 77 -79.
  • Mashhoor.K, Kottickal,L.V, Shanas,S.and Ramesh.N, Genetic structure and phylogenetic status of rice black bug, scotinophara bispinosa (Hemiptera: Pentatomidae). Journal of Agricultural Technology 2013, Vol. 9(6):1447-14521447.
  • E. R. Chaithanya, Rosamma Philip, Naveen Sathyan, and P. R. Anil Kumar, Molecular Characterization and Phylogenetic Analysis of a Histone-Derived Antimicrobial Peptide Teleostin from the Marine Teleost Fishes, Tachysurus jella and Cynoglossus semifasciatus. ISRN Molecular Biology,Volume 2013 (2013), Article ID 185807, 7 pages.
  • Ann Rose Bright, Naveen Sathyan, Swapna P. Antony, T.J.James, Rosamma Philip, Phylogeny and genetic divergence of three phenotypic variants of the ornamental goldfish, Carassius auratus (Linnaeus, 1758) based on CO1 gene. International Journal of Research in Zoology 2013; 3(1): 4-9, ISSN 2278 –1358.
  • P. Valarmathi.R, Rabindran.R, Velazhahan.S, Suresh.S, Robin, First report of Rice orange leaf disease phytoplasma (16 SrI) in rice (Oryza sativa) in India. Australasian Plant Pathology Society Inc. 2013 10.1007/s13314-013-0117-7.
  • E. R. Chaithanya, Rosamma Philip, Naveen Sathyan, P. R. Anil Kumar, Swapna P. Antony, V. N. Sanjeevan, I. S. Bright Singh, A Novel Isoform of the Hepatic Antimicrobial Peptide, Hepcidin (Hepc-CB1), from a Deep-Sea Fish, the Spinyjaw Greeneye Chlorophthalmus bicornis (Norman, 1939). Molecular Characterisation and Phylogeny. Probiotics and Antimicrobial Proteins, March 2013, Volume 5, Issue 1, pp 1-7.
  • Naveen Chandra Suryadevara,Venkata Sanjeev Kumar Neela, Kamakshi Prudhula Devalraju, Suman Jain, Krovvidi S.R. SivaSai, Vijaya Lakshmi Valluri, Subbanna Jonnalagada, MPJS Anandaraj, Influence of Intron II microsatellite polymorphism in human toll-like receptor 2 gene in leprosy. Human Immunology,Volume 74, Issue 8, August 2013, Pages 1034–1040.
  • John Lijo, Panicker Varuna P, George Sisilamma, Polymorphism analysis of Hsp70 gene in chicken and duck. Indian Journal of Poultry ScienceYear : 2012, Volume : 47, Issue : 2, p-129-135, ISSN : 0974-8180.
  • J. Kiruthika, S. Rajesh, A.G. Ponniah, M.S. Shekhar, Molecular cloning and characterization of acyl-CoA binding protein (ACBP) gene from shrimp Penaeus monodon exposed to salinity stress. Developmental & Comparative Immunology, Volume 40, Issue 1, May 2013, Pages 78–82.
  • Mohammad Zeeshan Najm1, Md Salman Akhtar2, Istaq Ahmad2, Sadaf4, Mohd NasarMallick2, Mohd Adnan Kausar1, Shilpi Chattopadhyay2, Amjid Ahad1, Shuaib Zaidi3, Syed Akhtar Husain2, Waseem Ahmad Siddiqui1, Mutational Analysis of Prohibitin – A Highly Conserved Gene in Indian Female Breast Cancer Cases. Asian Pacific Journal of Cancer Prevention, Vol 13, 2012, DOI:
  • M.S. Shekhar, J. Kiruthika, A.G. Ponniah, Identification and expression analysis of differentially expressed genes from shrimp (Penaeus monodon) in response to low salinity stress. Fish & Shellfish Immunology,Volume 35, Issue 6, December 2013, Pages 1957–1968.
  • Suma Arun Dev, E. M. Muralidharan, P. Sujanapal, M. Balasundaran, Identification of market adulterants in East Indian sandalwood using DNA barcoding. Annals of Forest Science, December 2013, DOI 10.1007/s13595-013-0354-0, ISSN 1297-966X.
  • V.V. Afsal, Swapna P. Antony, Ann Rose Bright, Rosamma Philip, Molecular identification and characterization of Type I crustin isoforms from the hemocytes of portunid crabs, Scylla tranquebarica and Portunus pelagicus. Cellular Immunology,Volume 284, Issues 1–2, July–August 2013, Pages 45–50.
  • E.R. Chaithanya, Rosamma Philip, Naveen Sathyan, P. R. Anil Kumar, Sherine Sonia Cubelio, I. S. Bright Singh, Molecular Characterisation and Phylogenetic Analysis of a Novel Isoform of Hepatic Antimicrobial Peptide, Hepcidin (Zc-hepc1), from the Coral Fish Moorish idol, Zanclus cornutus (Linnaeus, 1758). Probiotics and Antimicrobial Proteins, September 2013, Volume 5, Issue 3, pp 187-194, DOI 10.1007/s12602-013-9139-x, ISSN 1867-1314.
  • Steven G. Newmaster, Subramanyam Ragupathy, Shanmughanandhan Dhivya, Chitilappilly Joseph Jijo, Ramalingam Sathishkumar, Kirit Patel, Genomic valorization of the fine scale classification of small millet landraces in southern India. Genome, 2013, 56(2): 123-127, 10.1139/gen-2012-0183.
  • Vijesh Kumar IP, Reena N, Anandaraj M, Eapen SJ, Johnson GK, et al. (2013) Amplification, Cloning and In silico Prediction of Full Length Elicitin Gene from Phytophthora capsici, the Causal Agent of Foot Rot Disease of Black Pepper.J Plant Pathol Microb 4: 181 doi:10.4172/2157-7471.100018.
  • Sanjoy Das, K. V. Lalitha, Nirmala Thampuran, Isolation and molecular characterisation of atypical enterotoxigenic Bacillus cereus with negative Voges-Proskauer reaction from Indian white shrimp Fenneropenaeus indicus (H. Milne Edwards, 1837). Indian J. Fish., 60(4) : 113-117, 2013.
  • Vinesh P.V, Biswajit Brahma, Rupinder Kaur, Tirtha Kumar Datta, Surender Lal Goswami, Sachinandan De, Characterization of β-casein gene in Indian riverine buffalo. Gene Volume 527, Issue 2, 25 September 2013, Pages 683–688.
  • Mridula Nambiarand Sathees C. Raghavan, G-Quadruplex Structures Formed at the HOX11 Breakpoint Region Contribute to Its Fragility during t(10;14) Translocation in T-Cell Leukemia Mol. Cell. Biol. 2013 33: 4266-4281.
  • Singaiah NaveenKumar, Malathi Shekar, Iddya Karunasagar, Indrani Karunasagar, Genetic analysis of RNA1and RNA2 of Macrobrachium rosenbergii nodavirus (MrNV) isolated from India. Virus Research Volume 173, Issue 2, May 2013, Pages 377–385.
  • Gautam Pareek, Vivekanandhan Krishnamoorthy and Patrick D'Silva, Molecular Insights Revealing Interaction of Tim23 and Channel Subunits of Presequence Translocase. 13Mol. Cell. Biol. December 2013vol. 33 no. 23 4641-4659,September 2013, doi:10.1128/MCB.00876.
  • Maqbool, Raihana; Ismail, Rehana; Mahboob-ul-Hussain, Mutations in MicroRNA Genes and Their Binding Sites are Infrequently Associated with Human Colorectal Cancer in the Kashmiri Population. Bentham Science Publishers, MicroRNA, Volume 2, Number 3, November 2013 , pp. 219-224(6).
  • Singaiah Naveen Kumar, Indrani Karunasagar ,Iddya Karunasagar, Protection of Macrobrachium rosenbergii against white tail disease by oral administration of bacterial expressed and encapsulated double-stranded RNA. Fish & Shellfish Immunology,Volume 35, Issue 3, September 2013, Pages 833–839.
  • S.C.R. Thumu and P.M. Halami, Phenotypic expression, molecular characterization and transferability of erythromycin resistance genes in Enterococcus spp. isolated from naturally fermented food. Journal of Applied Microbiology , March 2014 Volume 116, Issue 3, pages 689–699 DOI: 10.1111/jam.12386.
  • M.K. Rajesh, B.A. Jerard, P. Preethi, Regi Jacob Thomas, T.P. Fayas, K.E. Rachana, Anitha Karun, Development of a RAPD-derived SCAR marker associated with tall-type palm trait in coconut. Scientia Horticulturae, Volume 150, 4 February 2013, Pages 312–316.
  • Akansha Bhatia, Sangeeta Madan, Jitendra Sahoo, Muntjeer Ali, Ranjana Pathania, Absar Ahmed Kazmi, Modak, A., Bhaumik, P. and Phale, P. S. (2014), Periplasmic glucose-binding protein fromPseudomonas putida CSV86 – identification of the glucose-binding pocket by homology-model-guided site-specific mutagenesis. FEBS Journal, 281: 365–375. doi: 10.1111/febs.12607.
  • Bhatia A et al., Diversity of bacterial isolates during full scale rotary drum composting. Waste Management, Volume 33, Issue 7, July 2013, Pages 1595–1601.
  • Krishnakumar Bhaskaran, Anupama Vijaya Nadaraja, Soumya Tumbath, Liji Babu Shah, Prajeesh Gangadharan Puthiya Veetil, Phytoremediation of perchlorate by free floating macrophytes: Journal of Hazardous Materials, Volume 260, 15 September 2013, Pages 901–906.
  • Rbin Kurian Abraham, R. A Pyron, Ansil B. R., Arun Zachriah & Anil Zachriah, Two novel genera and one new species of treefrog (Anura: Rhacophoridae) highlight cryptic diversity in the Western Ghats of India. Zootaxa. 3640 (2): 177–189.
  • Sheela Thankakkon and Patterson Edward, J.K., Molecular Phylogenetic analysis of two closely related marine Indian mussels of Genus Perna (PHILIPSSON, 1788) based on mitochondrial (COI) and nuclear (ITS) genes. Journal of Aquatic Biology & Fisheries, Vol. 1(1 & 2) 2013 : 123-139
  • V.V. Afsal, Swapna P. Antony, V.N. Sanjeevan, P.R. Anil Kumar, I.S. Bright Singhc, Rosamma Philip. A new isoform of anti-lipopolysaccharide factor identified from the blue swimmer crab, Portunus pelagicus: Molecular characteristics and phylogeny. Aquaculture, Volumes 356–357, 1 August 2012, Pages 119–122.
  • V.V. Afsal, Swapna P. Antony, E.R. Chaithanya, I.S. Bright Singh, Rosamma Philip, Two isoforms of anti-lipopolysaccharide factors identified and characterized from the hemocytes of portunid crabs, Portunus pelagicus and Scylla tranquebarica. Molecular Immunology,Volume 52, Issues 3–4, October–December 2012, Pages 258–263.
  • Abani Kanta Naik, Sathees C. Raghavan, Differential Reaction Kinetics, Cleavage Complex Formation, and Nonamer Binding Domain Dependence Dictate the Structure-Specific and Sequence-Specific Nuclease Activity of RAGs. Journal of Molecular Biology,Volume 415, Issue 3, 20 January 2012, Pages 475–488.
  • Mridula Nambiar and Sathees C. Raghavan, Mechanism of Fragility at BCL2 Gene Minor Breakpoint Cluster Region during t(14;18) Chromosomal Translocation. The Journal of Biological Chemistry, 2012 287, 8688-8701.
  • Mahesh Kappanayil, Sheela Nampoothiri, Rajesh Kannan, Marjolijn Renard, Paul Coucke, Fransiska Malfait,Swapna Menon, Hiran K Ravindran, Renu Kurup, Muhammed F Haque, Krishna Kumar and Anne DePaepe, Characterization of a distinct lethal arteriopathy syndrome in twenty-two infants associated with an identical, novel mutation in FBLN4 gene, confirms fibulin-4 as a critical determinant of human vascular elastogenesis. Orphanet Journal of Rare Diseases, 2012 7:61 doi:10.1186/1750-1172-7-61.
  • Ajaz Ahmad Waza, Khurshid Andrabi, Mahboob Ul Hussain, Adenosine-triphosphate-sensitive K+channel (Kir6.1): A novel phosphospecific interaction partner of connexin 43 (Cx43). Experimental Cell Research, Volume 318, Issue 20, 10 December 2012, Pages 2559–2566.
  • Prajeesh Gangadharan Puthiya Veetil, Anupama Vijaya Nadaraja, Arya Bhasi, Sudheer Khan, Krishnakumar Bhaskaran, Degradation of Triclosan under Aerobic, Anoxic, and Anaerobic Conditions. Applied Biochemistry and Biotechnology, July 2012, Volume 167, Issue 6, pp 1603-1612.
  • Sandeep Kumar, Virendra K. Baranwal, Priyanka Singh, Rakesh K. Jain, Sanjay D. Sawant, Sanjay K. Singh Characterization of a Grapevine leafroll-associated virus 3 from India showing incongruence in its phylogeny. Virus Genes, August 2012, Volume 45, Issue 1, pp 195-200.
  • Sowmya Pazhur Mohandas, Sita Ravikumar, Sumi J Menachery, Gayathri Suseelan, Sai Shyam Narayanan, Hemaraj Nandanwar, Kesavan Madhavan Nampoothiri, Bioactives of Microbes Isolated from Western Ghat Belt of Kerala Show β-Lactamase Inhibition along with Wide Spectrum Antimicrobial Activity. Applied Biochemistry and Biotechnology July 2012, Volume 167, Issue 6, pp 1753-1762.
  • Naveen Sathyan, Rosamma Philip E.R. Chaithanya, P.R. Anil Kumar, Swapna P. Antony Identification of a histone derived, putative antimicrobial peptide Himanturin from round whip ray Himantura pastinacoides and its phylogenetic significance. Results in Immunology, Volume 2, 2012, Pages 120–124.
  • C.Durga Rao, Prasanna Yergolkar, and K. Subbanna Shankarappa, Antigenic Diversity of Enteroviruses Associated with Nonpolio Acute Flaccid Paralysis, India, 2007–2009. Emerg Infect Dis [Internet]. 2012
  • Naveen Sathyan, Rosamma Philip, E. R. Chaithanya, and P. R. Anil Kumar, Identification and Molecular Characterization of Molluskin, a Histone-H2A-Derived Antimicrobial Peptide from Molluscs. SRN Molecular Biology, Volume 2012 (2012), Article ID 219656, 6 pages,doi:10.5402/2012/219656.
  • E.R. Chaithanya, Rosamma Philip, Naveen Sathyan, P. R. Anil Kumar, Swapna P. Antony, V. N. Sanjeevan, I. S. Bright Singh, A Novel Isoform of the Hepatic Antimicrobial Peptide, Hepcidin (Hepc-CB1), from a Deep-Sea Fish, the Spinyjaw Greeneye Chlorophthalmus bicornis (Norman, 1939): Molecular Characterisation and Phylogeny. Probiotics and Antimicrobial Proteins, November 2012.
  • P. V. Suresh, Biodegradation of shrimp processing bio-waste and concomitant production of chitinase enzyme and N-acetyl-D-glucosamine by marine bacteria: production and process optimization. World Journal of Microbiology and Biotechnology, October 2012, Volume 28, Issue 10, pp 2945-2962.
  • M.S. Ghayal, M.T. Pandya, Microalgae Biomass: A Renewable Source of Energy. Energy Procedia. Volume 32, 2013, Pages 242–250.
  • V.V. Afsal, Swapna P. Antony, Naveen Sathyan, Rosamma Philip, Molecular characterization and phylogenetic analysis of two antimicrobial peptides: Anti-lipopolysaccharide factor and crustin from the brown mud crab, Scylla serrata. Results in Immunology,Volume 1, Issue 1, May 2011, Pages 6–10.
  • S. Rajesh, J. Kiruthika, A.G. Ponniah, M.S. Shekhar, Identification, cloning and expression analysis of Catechol-O-methyltransferase (COMT) gene from shrimp, Penaeus monodon and its relevance to salinity stress. Fish & Shellfish Immunology,Volume 32, Issue 5, May 2012, Pages 693–699.
  • Magesh H, Kamatchi C, Vaidyanathan R, Sumathi G. Identification of plasmid-mediated quinolone resistance genes qnrA1, qnrB1 and aac(6')-1b-cr in a multiple drug-resistant isolate ofKlebsiella pneumoniae. Indian J Med Microbiol 2011;29:262-8.
  • Swapna P. Antony, I.S. Bright Singh, Rosamma Philip, Molecular characterization and phylogenetic analysis of a penaeidin-like antimicrobial peptide, Fi-penaeidin fromFenneropenaeus indicus, Aquaculture. Volume 319, Issues 1–2, 1 September 2011, Pages 298–301.
  • Ushasree Mrudula Vasudevan, Sumayya Husaiba Beevi Salim and Ashok Pandey: A Comparative Analysis of Recombinant Expression and Solubility Screening of Two Phytases in E. coli, Recombinant Expression of E. coli Phytases. Food Technol. Biotechnol. 49 (3) 304–309 (2011).
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